A deadly collision between a car and van has killed two people on Highway 17 between Massey and Espanola.  OPP say two people in the car died when their vehicle was hit by a van that crossed the centre line.  Two passengers in the car and the driver of the van are in hospital with serious injuries.  The crash took place just after 11:00pm Tuesday and closed the highway completely until if fully re-opened around 8:00 am Wednesday.  No names have been released while police notify next of kin.  The investigation continues.